excipients: meglumin, benzalkonium chloride, propylene glycol.
Dosage form. Liniment.
Basic physical and chemical properties: clear yellow liquid with a weak specific smell.
Pharmacotherapeutic group. Adjuvants. Code ATX L03A X.
Cycloferon refers to the immunomodulatory and antiviral drugs. The drug is a high molecular weight inducer of the formation of endogenous interferon. The effectiveness of the drug is associated with a broad spectrum of biological activity: anti-inflammatory, antiproliferative, antiviral, immunomodulatory, antitumor effect. Cycloferon when introduced into the body potentiates the formation and maintenance of tissues and organs high titers of beta - and alpha-interferons.
Particularly high content of interferons is determined in tissues and organs containing a large amount of lymphoid elements in the liver, spleen, lungs, mucous membrane of the intestine. The drug activates the stem cells of the bone marrow, causing the rapid formation of granulocytes. Normalizes the ratio of T-helpers and T-suppressors, promotes activation of killer cells and T-lymphocytes. Immunodeficiency of various origins that causes the correction of the immune status of the organism. Able to penetrate the blood-brain barrier.
Cycloferon induces clinical improvement in viral infectious diseases (herpes, influenza, encephalitis, hepatitis, cytomegalovirus infection, HIV infection, papillomatous and enterovirus infection). Thanks to the activation of the immune system has protivodiareynoe and antimicrobial activity. Prevents the formation in the organism of neoplastic processes as a result of cancer and antimetastatic actions. Suppresses the autoimmune response of the body that is manifested by a decrease in the severity of pain and inflammation in systemic connective tissue diseases and rheumatic diseases.
The local application of Cycloferon leads to improved balance of the immune system, possesses anti-proliferative and anti-inflammatory action.
After taking internally of Cycloferon in the maximum allowable dosage of active substance is detected in maximum plasma concentrations in 2-3 hours. Further concentration of the drug decreases to 8 hours. A day after receiving Cycloferon can be detected in the body in trace concentrations. The half-life is 4-5 hours. In the appointment of Cycloferon in the recommended dosage of cumulation of the active substance is not observed.
Indications for use
Cicloferon for parenteral use
For adults in the complex therapy for:
• HIV clinical stage 2A-3B,
• viral hepatitis A, D and b,
• systemic diseases of connective tissue and rheumatic diseases (systemic lupus erythematosus, rheumatoid arthritis),
• neuroinfections (including borellis tick-borne Lyme disease, serous meningitis, encephalitis),
• cytomegalovirus or herpes infection,
• secondary immunodeficiency due to chronic or acute fungal and bacterial infections
• chlamydial infections
• degenerative joint disease (including osteoarthritis deformans).
In paediatrics (children over 4 years) - in the complex therapy for:
• viral hepatitis, A, D, GP and b
• herpes infection,
• HIV clinical stage 2A-3B.
• For internal ingestion and parenteral administration, liver cirrhosis (decompensated),
• allergic reaction to the cycloferon and other components of the tool.
Cycloferon is contraindicated for pregnant women and breastfeeding mothers. During lactation is not contraindicated can liniment of cycloferon.
The drug is fully compatible with other drugs, which are prescribed in the treatment of these diseases (including chemotherapy and interferon).
No information available.
Cycloferon solution for injection in ampoules of 2 ml (12,5%). In the vial – yellow liquid, transparent. 1 ml solution for injection contains 125 mg (1 ampoule – 250 mg). In a carton box 5 ampoules in a contour package.
Cycloferon is recommended to store in a protected from light, dry place at a temperature of 18-20°C. the Pills and liniment to keep no more than 2 years; solution for injection: 3 years. A short-term freeze solution for injection (during transport) – this does not change the medicinal and physicochemical properties of the drug. The frozen solution for injection should be thawed only at room temperature. In the case of formation of precipitate or change of color of the solution for injection drug use is impossible.
Injection of Cycloferon
Active ingredients: criconematina acid (125 mg in 1 ml 250 mg in 1 ampoule).
Inactive ingredients: water for injections, a stabilizing salt and an additive (N-methylglucamine 192,9 mg in 2 ml).
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