DIANE 35 . About the drug:
Combined preparation containing estrogen - ethinyl estradiol and antiandrogen cyproterone acetate has progestational properties.
Indications and dosage:
The prevention of pregnancy in women with symptoms of androgenization (the appearance of women have male traits caused by male sex hormones). Phenomena androgenization (acne acne, seborrhea, mild forms of androgenetic alopecia, baldness in women, under the action of male sex hormones, hirsutism, excess body hair in women male pattern).
To prevent pregnancy during the first cycle of treatment every day take 1 tablet with 5-th to 25-th day of menstrual cycle counting 1st day of menstruation is the first day of the cycle. Then after 5-day break, during which there is bleeding, start taking the next pack (21 pills) of the drug.
The risk of cardiovascular complications increases with Smoking (especially after 35). Before taking the drug, and regularly against the background of its application required consultation. Taking the drug immediately terminated in case of occurrence of the following symptoms: early signs of phlebitis (inflammation of the vein wall), thrombosis (clogging of blood vessels by blood clot), embolism (violations of vascular permeability) - swelling of veins, unusual pain in the legs, pain in the chest when breathing or coughing, the feeling of pressure in the chest; first appeared migrenepodobnykh headaches, sudden hearing and vision, motor dysfunction. The stops taking the drug 6 weeks prior to planned surgery. The risk of thrombosis increases when high blood pressure. Drug overturned in hepatitis, jaundice, itching, cholestasis (stagnation of bile in the bile ducts), frequent epileptic seizures, primary or secondary occurrence of porphyria (a disease associated with metabolic disorders of porphyrin /pigments/). While the use of barbiturates, rifampicin, ampicillin, griseofulvin, butadiene, antiepileptic drugs efficacy of the drug is reduced. While taking the drug on the background antidiabetic therapy may change glucose tolerance (glucose tolerance).
Vomiting or diarrhea can result in excretion of drugs from the body, therefore, in those cases when these symptoms disappear within 1 day, a pill must be taken repeatedly. With more long-term conservation of these symptoms should temporarily resort to other methods of contraception.
Serious side effects overdose have been reported.
Symptoms: nausea, vomiting and slight vaginal bleeding (in young girls).
Treatment: symptomatic. There is no specific antidote.
A feeling of pressure in the chest
Changes in body weight and libido
Depression (state of despondency)
Chloasma (yellowish-brown spots on the skin)
Severe headaches (migraines)
Acute visual disturbances
The first symptoms of thrombophlebitis (inflammation of the walls of veins with their occlusion) or tromboamboliceski phenomena (impaired patency of the vessels)
The appearance of jaundice
Strong increase in blood pressure
Idiopathic jaundice or severe pruritus during pregnancy in anamnese (formerly)
Syndromes Dubin-Johnson (hereditary liver disease accompanied by jaundice) and Rotor (hereditary liver disease characterized by moderate increase in the blood bilirubin)
Cancer of the breast or endometrium (inner layer of uterus)
Vesicular dermatosis (skin disease) during pregnancy in history
Otosclerosis (progressive hearing loss and tinnitus) with deterioration during previous pregnancies
Interaction with other medications and alcohol:
Some medicines can reduce the efficacy of Diane-35. These include drugs used to treat epilepsy (for example, primidon, phenytoin, barbiturates), tuberculosis (e.g., reef-picin); antibiotics to treat certain infectious diseases (e.g. ampicillin, tetracyclines, griseofulvin). Always inform the doctor who prescribes you Diane-35 what medicines you are already taking. Also tell any physician who prescribes other drugs, as well as the pharmacist recommending you medicines at the pharmacy that you are taking Diane-35.
Composition and properties:
Each tablet of Diane-35 contains:
Cyproterone acetate 2.0 mg;
Ethinylestradiol - 0.035 mg.
Lactose monohydrate, corn starch, polyvidon - 25000, magnesium stearate, sucrose, polyvidone - 700000, macrogol - 6000, precipitated calcium carbonate, talc, glycerol 85%, titanium dioxide, iron oxide yellow, iron oxide red, metallically wax.
Form of issue:
Diane-35 is available in a calendar pack of 21 tablets. Pills Diane-35 are in a blister pack: cells are made of polyvinylchoride film and aluminum foil coated with a coating.
The preparation retains a high viscosity of cervical mucus, which hinders the penetration of sperm into the uterine cavity and contributes to the contraceptive effect. Cyproterone acetate blocks androgen receptors and reduces the effect of androgenization in women (increased production of sebum, hair growth male pattern hair loss on the head). On the background of treatment with the drug reduced the symptoms of acne, prevented the appearance of new acne. Along with antiandrogen properties, cyproterone acetate has progestational activity, which leads to inhibition of ovulation and accordingly the contraceptive effect. The contraceptive effect of Diane-35 is manifested by the 14th day from the start of administration and lasts for a period of 7-day pauses in use.
Storage conditions: in the dark place.